Surface marker and other characteristics of Gaucher's cells.
نویسندگان
چکیده
A full surface marker study of the splenic storage cells in a case of Gaucher's disease largely substantiates the monocyte/histiocyte nature of Gaucher's cells. In addition, an apparent T-lymphocyte deficiency is demonstrated in the spleen and peripheral blood, and the possible significance of this finding is discussed.
منابع مشابه
Gaucher's cells
Gaucher's cells have been extensively investigated morphologically and biochemically, and it is now thought that they represent histiocytic cells in which large amounts of glucocerebroside have accumulated because of a deficiency of ,B-glucosidase (Brady, 1972). The histiocytic nature of Gaucher's cells has been inferred from their phagocytic ability (Lee et al., 1967), high lysosomal enzyme co...
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ورودعنوان ژورنال:
- Journal of clinical pathology
دوره 30 10 شماره
صفحات -
تاریخ انتشار 1977